--- slug: regenerative-frontier --- # Regenerative and Frontier Clinic-administered and frontier therapies: therapeutic plasma exchange, hyperbaric oxygen, photobiomodulation, stem cells, exosomes, peptides, gene therapy tourism, IV NAD+. This is where the gap between mechanism and human outcomes matters most. Start with [Therapeutic Plasma Exchange and Plasma Dilution](plasma-exchange-dilution.md) for the section's core rule: a procedure can be real, technical, and biologically plausible while still lacking clinical longevity-outcome proof. Then read [Hyperbaric Oxygen Therapy (HBOT)](hyperbaric-oxygen-therapy.md) for the oxygen-exposure version of the same problem: a legitimate clinical device protocol with small human RCT signals, a large wellness-market halo, and no proved healthy-lifespan endpoint. [Photobiomodulation (Red and Near-Infrared Light)](red-nir-photobiomodulation.md) brings that discipline to the consumer-device edge, where wavelength and dose details matter more than the generic "red light" label. [Stem Cell Therapy (Allogeneic MSC, Autologous SVF)](stem-cell-therapy.md) and [Exosomes](exosomes.md) extend the same standard to cellular and cell-derived products, where selected disease-specific approvals coexist with systemic packages that operate on case-series-tier evidence and a shifting regulatory map. [Peptide Therapeutics](peptide-therapeutics.md) applies the same discipline to molecule-specific clinic protocols, unstable compounding status, research-use markets, and the gap between mechanistic repair stories and human outcome evidence. [Gene Therapy Tourism](gene-therapy-tourism.md) and [Intravenous NAD+ and Oral NAD+ Precursors](nad-precursor-protocols.md) mark the far edge of the section: high-cost interventions where mechanism, access, and human outcome evidence have to be separated before anyone can judge the claim. Read straight through, or land on a specific entry and follow its outgoing links into adjacent interventions, diagnostics, and failure modes. --- - [Next: Therapeutic Plasma Exchange and Plasma Dilution](plasma-exchange-dilution.md) - [Previous: Low-Dose Tadalafil (Off-Label Longevity Use)](tadalafil-longevity-use.md)